Seemingly unstoppable in Serie A, the Old Lady was brought to her knees in the Champions League at Highbury on Tuesday where they suffered a 2-0 defeat to Arsenal in the first leg of their quarterfinal.

The result has left Juve with a mountain to climb in the second leg next Wednesday and could have a knock-on effect on their league form for the remaining seven games of the season.

Despite their 1-1 draw with Roma last week, Juve still have an eight-point cushion at the top of the table and few would bet against them landing a 29th Scudetto.

But although the reigning champions are still firmly in the driving seat, AC Milan coach Carlo Ancelotti knows only too well that miracles can happen in football, having been the victim of the greatest fightback in Serie A history.

Ancelotti was in charge of Juventus for the 1999/2000 season when they built up a nine-point lead with eight games to go, only to lose the title to Sven-Goran Eriksson's Lazio on the final day.

"Anything is possible as I learned when I was at Juve," said Ancelotti, whose Milan side are well placed to reach the semi-finals of the Champions League after their goalless draw at Lyon.

Juventus coach Fabio Capello is likely to rotate his squad for the trip to Treviso with one eye on the Arsenal match in Turin.

Pavel Nedved is unavailable following his red card against Roma, so Adrian Mutu is likely to continue in the Czech midfielder's place.

Treviso, 14 points adrift of fourth from bottom Udinese, are almost certain for a swift return to Serie B, together with Lecce, Milan's opponents this weekend.

Inter, five points behind city rivals Milan in third place, entertain Messina this weekend, boosted by their impressive comeback in the Champions League.

Fiorentina host Roma in what is effectively a play-off for the fourth and final Champions League place.